27-hydroxycholesterol causes cognitive deficits by disturbing Th17/Treg balance and the related immune responses in mild cognitive impairment patients and C57BL/6J mice

Table 6 FDI and TDI values of mice after intervention (n = 10 mice/group)

Frequency identification index (FDI) = (Fn − Ff)/(Fn + Ff), time discrimination index (TDI) = (Tn − Tf)/(Tn + Tf) (Fn: exploring frequency of novel object; Tn: exploring time of novel object; Ff: exploring frequency of familiar object; Tf: exploring time of familiar object); SR1001: inhibitor of RORγt; P60: inhibitor of Foxp3; 27-OHC: 27-hydroxycholesterol

ISSN: 1742-2094