Skip to main content
Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Hypochlorous acid derived from microglial myeloperoxidase could mediate high-mobility group box 1 release from neurons to amplify brain damage in cerebral ischemia–reperfusion injury

Fig. 10

Schematic diagram showing that microglia-derived myeloperoxidase (MPO) can be transferred into neuron through exosomes, increasing the MPO and HOCl production in neuron. HOCl facilitates active cytoplasmic translocation and secretion of HMGB1 in the disulfide form, promoting inflammation and aggravating brain damage

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094