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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Hypochlorous acid derived from microglial myeloperoxidase could mediate high-mobility group box 1 release from neurons to amplify brain damage in cerebral ischemia–reperfusion injury

Fig. 9

Plasma HOCl level was correlated with the severity of infarct volume and neurological deficit scores in ischemic stroke patients. A Representative CT scanning images showing the infarct area of the ischemic stroke patients (white arrow). B Using HKOCl-3 to detect plasma HOCl levels in ischemic stroke patients and healthy controls. C Plasma HOCl levels in different groups correspond to minor, moderate and large infarction sizes of ischemic stroke patients and healthy volunteers. D Pearson correlation coefficients of plasma HOCl level and infarct volume in acute ischemic stroke patients. E Pearson correlation coefficients of plasma HOCl level and NIHSS in acute ischemic stroke patients. All data are presented as mean ± SEM. (Statistical methods: A two-tailed t-test; C one-way ANOVA followed by Bonferroni multiple comparisons test; D, E Pearson correlation coefficient.)

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