Fig. 7

Microglial analysis. Charts showing the density of microglial subpopulations, with either the reactive (Iba1⁺CD45⁺; A pro-inflammatory (Iba1⁺CD16/CD32⁺; B or anti-inflammatory phenotype (Iba1⁺CD206⁺; C Note that surgery reduces the density of reactive microglia, which is restored by IMC transplantation, and the increase in anti-inflammatory neuroprotective microglia. Moreover, both deleterious and neuroprotective effects are focused on lobes IV–V (affected by surgery) and X (neuro-resistant). Data are expressed as mean ± SEM and the statistical analyses were performed using the Ln of represented values for their normalization. For comparing the lobes of all three experimental groups individually: *p < 0.05, **p < 0.01. For comparing the lobes of each experimental group: ^#p < 0.05, ^##p < 0.01, for differences with lobe VIII (neutral); ^$p < 0.05, ^$$p < 0.01, for differences between lobes IV–V and X