Fig. 2
From: Modeling the neuroimmune system in Alzheimer’s and Parkinson’s diseases
Comparison of healthy versus pathological neuroimmune system: in healthy neuroimmune system (1) microglia are in a homeostatic and surveillant state, (2) with limited infiltration of peripheral immune cells into the central nervous system. In the pathological neuroimmune system, (3) microglia become reactive and display an altered morphology, with increase of (4) phagocytosis, (5) inflammatory markers and (6) peripheral immune cell infiltration. Image created with BioRender.com