Fig. 5
Single-cell RNA sequencing analysis shows distinctive transcriptomics of blood monocytes treated with Cl-LPM compared to control at 1Â dpi. ScRNAseq was performed on monocytes isolated from blood of mice pre-treated with Cl-LPM or Control-LPM at 1Â dpi. A Heatmap plotting of the top 15 up and down differentially expressed genes from CL-LPM compared to control-LPM pre-treated mice. B Violin plots of selected genes differentially expressed in CL-LPM monocytes vs control-LPM. C Enhanced volcano plot of DGEs. D GO plot shows top 10 relevant GO pathways related to all significant up and down regulated genes in CL-LPM relative to control monocytes