Table 3 Optimal models to predict clinical multiple sclerosis versus non-multiple sclerosis status
From: Combination protein biomarkers predict multiple sclerosis diagnosis and outcomes
Category | Biomarkers | N | Markers | AUC train | AUC test |
|---|---|---|---|---|---|
CSF | TCC + C9 + Ch3L1 + TNFR1 + sCD27 | 157 | 5 | 0.96 | 0.94 |
Serum | iC3b + CCL27 + osteopontin + MCP1 | 148 | 4 | 0.93 | 0.91 |
CSF/serum | CSF[Ch3L1+ TNFR1 + sCD27] + serum[osteopontin + MCP1] | 157 | 5 | 0.97 | 0.97 |