Table 2 Summary of donor information from cohorts used in drug studies
From: Advanced patient-specific microglia cell models for pre-clinical studies in Alzheimer’s disease
Study cohorts used in drug studies | Healthy control (HC) | Alzheimer’s disease (AD) | |
|---|---|---|---|
N° of participants | n = 5 | n = 8 | |
Sex of participants | Females (%) | 60% (3/5) | 75% (6/8) |
Males (%) | 40% (2/5) | 25% (2/8) | |
Age of participants (mean ± SD) | 69.4 ± 2.5 | 68.5 ± 6.4 | |
APOE genotype | E3/E3 (%) | 20% (1/5) | 0% (0/8) |
E3/E4 (%) | 60% (3/5) | 75% (6/8) | |
E4/E4 (%) | 20% (1/5) | 25% (2/8) | |