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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Integration of National Health Insurance claims data and animal models reveals fexofenadine as a promising repurposed drug for Parkinson’s disease

Fig. 3

Fexofenadine ameliorates microgliosis in 6-OHDA mouse model. IHC of IBA-1 in Cpu and SN in PBS, PBS + Fexo, 6-OHDA, or 6-OHDA + Fexo. Values are derived from the analyzed density of IBA-1 positive cell density/mm2 in Cpu and SN in PBS (n = 14), PBS + Fexo (n = 5), 6-OHDA (n = 12), or 6-OHDA + Fexo groups (n = 18). Scale bar indicates 50 μm. ***p < 0.001, **p < 0.01, two-way ANOVA with Tukey’s multiple comparison test

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