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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Integration of National Health Insurance claims data and animal models reveals fexofenadine as a promising repurposed drug for Parkinson’s disease

Fig. 8

Fexofenadine alleviates the infiltration of peripheral immune cells. a Graph obtained from RT-PCR analysis performed on the cortex from M83 Tg mice, which were treated with PBS (n = 3), PFF (n = 5), and PFF + Fexo (n = 4 or 5). **p < 0.01, *p < 0.05, one-way ANOVA with Tukey’s multiple comparison test. b IHC of CD3 in the ipsilateral M2, Cpu, Ect, BLA, and Ent of M83 Tg mice brain. Values are derived from the analysis of data collected from PBS (n = 3), PFF (n = 6) or PFF + Fexo (n = 4) groups. ***p < 0.001, **p < 0.01, * p < 0.05, two-way ANOVA with Tukey’s multiple comparison test. c IHC of F4/80 in ipsilateral M2, Cpu, Ect, BLA, and SN of M83 Tg mice brain. Values are derived from the analysis of data collected from PBS (n = 3), PFF (n = 4) or PFF + Fexo (n = 4) groups

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Journal of Neuroinflammation

ISSN: 1742-2094