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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: The insular cortex is not insular in thyroid eye disease: neuroimaging revelations of central–peripheral system interaction

Fig. 4

The correlation analysis and receiver operating characteristic curves for diagnosing the immunoendocrine status. A The correlation analysis results between all neurobiomarkers and immunoendocrine markers in AP. B The correlation analysis results between all neurobiomarkers and immunoendocrine markers in IP. C The receiver operating characteristic curves for diagnosing the immunoendocrine status of TED based on neurobiomarkers. The analysis revealed that the combination of activity of the insular cortex and the functional connectivity of insula-cerebellum demonstrated optimal diagnostic performance for immunoendocrine status (AUC = 0.81). ALFF: amplitude of low-frequency fluctuations; FC: functional connectivity; INS.R: right insular cortex; CER.L: left cerebellum 6; CER.R: right cerebellum 6; TSH: thyroid-stimulating hormone; fT3: free triiodothyronine; fT4: free thyroxine; TRAb: thyroid-stimulating hormone receptor antibody; CD: the cluster of differentiation; AUC: area under curve

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Journal of Neuroinflammation

ISSN: 1742-2094