Fig. 2

Short-term oral DMF administration affects the expression of neuroinflammatory molecules in glial cells of App-KI mice. A Schematic protocol for the oral administration of DMF and isolation of microglia and astrocytes using MACS. Six-month-old WT or App-KI mice were orally administered with DMF or vehicle control for 1 month. B, C mRNA expression levels in MACS-isolated microglia (B) and astrocytes (C) from DMF- or vehicle-administered WT and App-KI mice determined by quantitative PCR. (n = 3, each group). Relative expression levels are plotted as means ± SEM. *p < 0.05, **p < 0.01 (two-way ANOVA)