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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury

Fig. 2

Changes in SPOCK2 expression and pain behaviors in rats after CCI. A, B PWT and PWL at baseline (day 0) and 1, 3, 7, 14, and 21 days after CCI or sham operation (*P < 0.05, **P < 0.01 vs baseline). C Time course of changes in SPOCK2 expression in the spinal cord in the sham group at 1, 3, 7, 14, and 21 days after CCI operation (*P < 0.05, **P < 0.01 vs sham). D Immunohistochemistry showing SPOCK2 localization in the spinal dorsal horn and increased ipsilateral expression at 14 days after CCI operation (Scale 50 um). Below column of images: higher power magnification of a section of the image on the top

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