Skip to main content
Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: P2X7 receptor antagonists modulate experimental autoimmune neuritis via regulation of NLRP3 inflammasome activation and Th17 and Th1 cell differentiation

Fig. 1

P2X7R expression in blood of patients with GBS and healthy controls. Human peripheral blood mononuclear cells (PBMCs) were isolated from blood samples, and P2X7R expression was examined using flow cytometry and qRT-PCR. (A) P2X7R mRNA levels were elevated in the PBMCs collected from patients with GBS compared to those in PBMCs collected from the healthy controls (n = 8 per group). (B-D) P2X7R expression increased on CD4+ T cells in the PBMCs collected from patients with GBS, but no significant increase was noted on CD8+ T cells or monocytes (CD14+) compared to healthy controls (n = 7 per group). HC, healthy control; GBS, Guillain–Barre Syndrome. *p < 0.05, **p < 0.01

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094