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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Microbiota-derived acetate attenuates neuroinflammation in rostral ventrolateral medulla of spontaneously hypertensive rats

Fig. 6

Acetate reduces blood-brain barrier (BBB) permeability in SHRs. A, assessment of BBB permeability by injection of Evans blue dye. B, OD620 readings of the brain tissues following Evans blue dye injection. C, application of small animal imaging to assess BBB permeability by injection of Cy5-Dextran (10 kDa). D, the relative Epi-fluorescence of brains in each group rats. n = 4 for each group. * P < 0.05, ** P < 0.01.E, transmission electron microscopic observation of vascular endothelial tight junction structure in the medulla of rats. The tight junctions between capillary endothelial cells are indicated by the arrows

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