Fig. 4

The influence of TGFβ1 on the Wnt-signaling molecules in ARPE-19 cells. The expression of Wnt signaling molecules was assessed by A RT-qPCR and B–G Western blot in ARPE-19 cells treated with TGFβ1 (10 ng/mL) for different time points within a time duration of 12 h. Dvl, dishevelled; FZD, frizzled receptor; h, hour (s); min, minutes; N, normal; ROR1, receptor tyrosine kinase-like orphan receptor 1; TGFβ1, transforming growth factor beta 1. All results performed above are presented as mean ± SEM from three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 compared with untreated ARPE-19 cells