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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: STING inhibition suppresses microglia-mediated synapses engulfment and alleviates motor functional deficits after stroke

Fig. 7

Antagonizing STING activation decreased the levels of phagocytosis-related molecules. A The relative mRNA levels of complete components after vehicle or H151 treatment at 7 days after surgery. B Heat map of the relative mRNA levels of phagocytic receptors. Darker color represented higher fold change. #P < 0.05, ##P < 0.01, ###P < 0.001, compared with sham + vehicle group; *P < 0.05, ***P < 0.001, compared with PT + vehicle group. C The fold change of mRNA levels of Rac2, Hmox1, and Pld4 after vehicle or H151 treatment. The results were relative to sham + vehicle group. n = 4–6 mice per condition. Data were presented as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001

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