Fig. 4
Blocking fibrin–CD11b interactions protects mice against TBI-related oxidative stress and neuronal injury. (A, B) Representative brain sections from 7d WT and 7d Fggγ390–396A mice stained for 4-HNE (A) or NeuN (B). Scale bars, 0.5 mm (A), 1 mm (B). Image quantification is shown. Data are presented as mean ± s.e.m.; n = 7–8 mice per group (1 mouse per point). *P < 0.05, ** P < 0.01 by two-tailed Mann-Whitney test (A) and two-way ANOVA with Bonferroni’s multiple comparisons test (B)