Fig. 3

Effects of Mas activation with AVE0991 on long-term outcomes after ICH. A The representative mouse open field test during test section. B, C Total distance and central distance in open field tests after ICH. D Representative heatmaps of the probe trial. D–F Escape latency, target quadrant and swim speed of Morris water maze after ICH. H Representative Nissl staining pictures in CA1 hippocampus at 28 days after ICH, scale bar1 = 100 μm, scale bar2 = 10 μm. I Quantitative analysis of surviving neurons in the CA1 area of the affected hippocampus at day 28 s after ICH. Data was represented as mean ± SD.**P < 0.01, ***P < 0.001 vs. Sham; ^#P < 0.05 vs. ICH + Vehicle, n = 6/group. Veh, Vehicle; AVE, AVE0991